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Subrahmanyam, E. V. S.
- Synthesis and Biological Studies of some Novel Thiazolidinones
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Authors
Affiliations
1 Department of Pharmaceutical Chemistry, NGSM Institute of Pharmaceutical Sciences, Paneer, Deralakatee - 574160, Mangalore, Karnataka, IN
1 Department of Pharmaceutical Chemistry, NGSM Institute of Pharmaceutical Sciences, Paneer, Deralakatee - 574160, Mangalore, Karnataka, IN
Source
Journal of Pharmaceutical Research, Vol 8, No 3 (2009), Pagination: 122-124Abstract
Pyridine-3-carboxylic acid hydrazide on condensation with substituted aromatic aldehydes yielded the benzylidine-arylidine acetohydrazido pyridine derivatives, (3a-3l) which on cyclization with thioglycolic acid in presence of anhyd. Zinc chloride as catalyst afforded phenyl-3-(Nicotinyl amino)-1, 3-thiazolidin-4-one derivatives (4a-4l). The structures of the newly synthesized compounds have been established on the basis of IR, MASS and 1H NMR spectral data. These compounds have also been screened for their biological activity.Keywords
Pyridine, 4-Thiazolidinone, Antibacterial, Antifungal.- Fatty Acids from Memecylon umbellatum (Burm.)
Abstract Views :133 |
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Authors
Himanshu Joshi
1,
Arun B. Joshi
1,
Hemlata Sati
2,
M. P. Gururaja
1,
Prajwal R. Shetty
1,
E. V. S. Subrahmanyam
1,
D. Satyanaryana
1
Affiliations
1 Dept. of Pharma. Chem., NGSM Institute of Pharmaceutical Sciences, Paneer, Deralakatte, Mangalore –574160, IN
2 Department of Pharmacy, H.N.B Garhwal University, Srinagar Garhwal, Uttaranchal, IN
1 Dept. of Pharma. Chem., NGSM Institute of Pharmaceutical Sciences, Paneer, Deralakatte, Mangalore –574160, IN
2 Department of Pharmacy, H.N.B Garhwal University, Srinagar Garhwal, Uttaranchal, IN